Conditions & Recovery · ScienceDaily — Cancer · June 2, 2026

A single protein may be holding back CAR T cancer therapy

A newly identified protein may be one of the biggest obstacles holding CAR T-cell therapy back. Researchers found that NFIL3 causes these engineered immune cells to become exhausted and lose their cancer-fighting power over time. When NFIL3 was disabled, the cells remained stronger for longer and controlled tumors more effectively in animal models.

Originally published by ScienceDaily — Cancer. We curate and add context; they did the reporting.

Related learning